How times change

[Scooter]

[Bicycle Bill]

So what's your point — stupid (from our current viewpoint) advertisements?  That's an ad from the early 1900s; over 100 years ago.  Even as recently as the post-WWII era, cigarettes companies had medicos shilling for their wares, with comments about how (brand name) was milder/more healthful/'better for your T-zone' than other (brand name).  This is no better than ridiculing medieval society for the beliefs that were prevalent in the Middle Ages.

-"BB"-

[RayThom]

Mommy, mommy... can I have more so I can stop shaking before the school bus gets here?

[Lord Jim]

ETA:

So what's your point — stupid (from our current viewpoint) advertisements? ...This is no better than ridiculing medieval society for the beliefs that were prevalent in the Middle Ages.

I think you're maybe taking this a little too seriously Bill...

I think it's interesting (and also to a certain extent amusing) to look back and see how advancing knowledge have changed popular beliefs over time...

[RayThom]

When I was a lad whenever we had a nasty toothache my parents has a box of small, brown, "throw pillow-shaped," pads that we would position at the pain site between the cheek and gum. I later found out that they contained morphine and they were left over from my father's BRN tour of duty during WWII.

They work great and I really missed them especially as I went through "petit mal withdrawal." Sigh!

[Big RR]

When my kids were teething I used to rub either whiskey or rum on their gums; it worked better than the medicine (that contained alcohol in glycerin) which was sold for the same purpose, and you didn't have to worry about what to do with the leftovers.

[dales]

ETOH was SOP for teething babies back in the day (my folks said it did the trick for me).

[Long Run]

I later found out that they contained morphine and they were left over from my father's BRN tour of duty during WWII.

Wow, that is a "back-in-the-day" story not every person gets to tell!

[rubato]

The trouble with cocaine is that the t1/2 is about 15 minutes.

Cocaine is metabolized into benzoylecognine by direct hydrolysis of an ester linkage.

yrs,
rubato

[dales]

The trouble with cocaine is that the t1/2 is about 15 minutes.

Cocaine is metabolized into benzoylecognine by direct hydrolysis of an ester linkage.

yrs,
rubato

[ex-khobar Andy]

The trouble with cocaine is that the t1/2 is about 15 minutes.

Cocaine is metabolized into benzoylecognine by direct hydrolysis of an ester linkage.

yrs,
rubato

The generally accepted half life of cocaine in the body is more like an hour. This paper gives considerably longer elimination half lives for various body fluids: "The mean (N = 6) plasma, saliva, and urine cocaine elimination half-lives were 1.5 +/- 0.1 h, 1.2 +/- 0.2 h, and 4.1 +/- 0.9 h, respectively." Obviously it depends on a number of factors, including individual metabolism characteristics. (I don't have a subscription to PubMed so I have read only the abstract.) . It's worth noting that the uppermost dose here was 2 g/day which is about a $150 a day habit based on a street price of $75 per gram.

[Gob]

Practice.

[rubato]

I was referring to the t 1/2 for the active form of the drug, not the excretion half life. But I have not worked in that area for 21 years. And the real point is that the effect is very short for either dental pain or recreational use so the user reaches the "want more" point frequently.



yrs,
rubato

[rubato]

While we're on the subject of beer. I was told that Guinness used to advertise by saying there is a baby in every bottle.





yrs,
rubato