Medical news.

[Darren]

ALS biomarker found in children’s teeth

"The researchers found the markers in the teeth of patients who went on to develop ALS as adults. They used lasers to map growth rings that form daily in the teeth and discovered evidence in the growth rings formed at birth and within the first 10 years of life that patients with ALS metabolized metals differently than patients without the disease."

https://neurosciencenews.com/als-teeth- ... jvwzcTVFpE

[RayThom]

ALS biomarker found in children’s teeth
"The researchers found the markers in the teeth of patients who went on to develop ALS as adults. They used lasers to map growth rings that form daily in the teeth and discovered evidence in the growth rings formed at birth and within the first 10 years of life that patients with ALS metabolized metals differently than patients without the disease."
https://neurosciencenew.com/als-teeth-1 ... jvwzcTVFpE

Wow, Darren, that's something.

This surely takes a bite out of this mystery disease.

As the son of an Englishman I had poor dental hygiene in my developmental years. Do you or Doc think it's possible this is the reason I have remained ALS free so far?

[Darren]

ALS biomarker found in children’s teeth
"The researchers found the markers in the teeth of patients who went on to develop ALS as adults. They used lasers to map growth rings that form daily in the teeth and discovered evidence in the growth rings formed at birth and within the first 10 years of life that patients with ALS metabolized metals differently than patients without the disease."
https://neurosciencenew.com/als-teeth-1 ... jvwzcTVFpE

Wow, Darren, that's something.

This surely takes a bite out of this mystery disease.

As the son of an Englishman I had poor dental hygiene in my developmental years. Do you or Doc think it's possible this is the reason I have remained ALS free so far?

I don't see the connection, Ray.

We've been trying to get a blood mineral panel test done for Doc. Even the local DO we use hasn't heard of it. I did find that Labcorp can do it using an outside lab. It's turned into a bit of a catch 22 because the doofi at Labcorp want the doctor to call them, but he doesn't have the time to screw with stuff like that, All I need is the test number.

Doc has several AI issues which the VA addresses in the usual "take two aspirin and come back in six months if you're still alive" fashion. If men aren't a priority for the "What you're still alive?" VA, women are even less of a priority.

I mentioned the gut biome to you previously. Research is finding more and more correlations with the gut biome and AI issues and possibly other disease with unknown causes.

[Darren]

"Sarcoidosis patients appear to have unusual energy production and transmethylation of proteins, as well as an abnormal gut microbiota, according to researchers at Wayne State University School of Medicine and colleagues, who compared the metabolites found in sarcoidosis patients with those of healthy people."

https://sarcoidosisnews.com/2016/08/15/ ... icrobiota/

[RayThom]

... "Sarcoidosis patients appear to have unusual energy production and transmethylation of proteins, as well as an abnormal gut microbiota, according to researchers at Wayne State University School of Medicine and colleagues, who compared the metabolites found in sarcoidosis patients with those of healthy people."
https://sarcoidosisnew.com/2016/08/15/s ... icrobiota/

Interesting.

What do they say about Hep 'C' or Cholera?

[Darren]

... "Sarcoidosis patients appear to have unusual energy production and transmethylation of proteins, as well as an abnormal gut microbiota, according to researchers at Wayne State University School of Medicine and colleagues, who compared the metabolites found in sarcoidosis patients with those of healthy people."
https://sarcoidosisnew.com/2016/08/15/s ... icrobiota/

Interesting.

What do they say about Hep 'C' or Cholera?

No clue about either.

"Furthermore, the restoration of gut microbiota can be a novel therapeutic modality to address the complexity of treatment in sarcoidosis. Bifidobacteria may be more suitable than lactobacillus for probiotics therapy for sarcoidosis."

https://www.atsjournals.org/doi/abs/10. ... acts.A1552

[RayThom]

... "Sarcoidosis patients appear to have unusual energy production and transmethylation of proteins, as well as an abnormal gut microbiota, according to researchers at Wayne State University School of Medicine and colleagues, who compared the metabolites found in sarcoidosis patients with those of healthy people."
https://sarcoidosisnew.com/2016/08/15/s ... icrobiota/

Interesting.
What do they say about Hep 'C' or Cholera?

No clue about either.
"Furthermore, the restoration of gut microbiota can be a novel therapeutic modality to address the complexity of treatment in sarcoidosis. Bifidobacteria may be more suitable than lactobacillus for probiotics therapy for sarcoidosis."
https://www.atsjournal.org/doi/abs/10.1 ... acts.A1552

Just more "circular information" from our Darren.

I'll check it out when I get 'round to it.

[Darren]

Interesting.
What do they say about Hep 'C' or Cholera?

No clue about either.
"Furthermore, the restoration of gut microbiota can be a novel therapeutic modality to address the complexity of treatment in sarcoidosis. Bifidobacteria may be more suitable than lactobacillus for probiotics therapy for sarcoidosis."
https://www.atsjournal.org/doi/abs/10.1 ... acts.A1552

Just more "circular information" from our Darren.

I'll check it out when I get 'round to it.

Ray, you missed the acorn in the article. It's leaky gut or if you want the fancy name, gut dysbiosis.

In a nutshell for whatever reason the mucous lining in your intestines is gone or damaged enough that stuff passes though your gut wall that shouldn't and in turn jacks up the immune response to the degree it attacks stuff like organs and tissues it shouldn't. If you have five or ten years left the newly minted MD's may be able to help you.

Until then the latest info your doctor most likely will get is the samples and pamphlets from the pharmaceutical reps that drop in daily to inform them of the newest drug on the block. You can either trust in the doctors that tell you there is no cure or you can look up your gut issue as explained and do yourself a favor.

While some of the doctors have heard about the gut microbiota at the VA, our experience is they're not going to look into it. That's why I said you'll have to survive long enough for medical schools to get their collective heads out of their asses and train a new generation of MDs.

You may also want to look for the link to cancer along with your AI issues. Cheers!

[RayThom]

... Ray, you missed the acorn in the article. It's leaky gut or if you want the fancy name, gut dysbiosis... If you have five or ten years left the newly minted MD's may be able to help you... You can either trust in the doctors that tell you there is no cure or you can look up your gut issue as explained and do yourself a favor... That's why I said you'll have to survive long enough for medical schools to get their collective heads out of their asses and train a new generation of MDs...
You may also want to look for the link to cancer along with your AI issues. Cheers!

Thank you so much, Doctor Darren. You supercilious pedant.

I missed nothing in your article. I was diagnosed with sarcoidosis in 1992. Do you think I've not stayed current with this disease in all that time? I discuss all of the latest treatments and diets -- including microbiome and drug therapy -- with my Internist PCP on an ongoing basis, so your pompous "finger shaking in my face" admonishment about missing your "acorn" was pointless and unnecessary, as is most of the info you dispense. We are currently figuring out what foods are most beneficial in maintaining my best health, especially since my stomach and some intestine were removed in my latest round of cancer surgery.

Darren, I suggest you stick with your silly brand of politics, and fantasies. That shit makes you look less stupid than most of the medical advice you prescribe.

Your "cut and paste" knowledge of everything under the sun is overwhelming. I'm curious, Darren, what do you really know? I'm guessing very little. You probably need two hands and a flashlight to find your asshole in the shower.

OK... you're dismissed.