Info from an ER doc. Good info on diagnosis & progresion

[Darren]

https://texags.com/forums/84/topics/310 ... 8k4tqrtO3w

[Scooter]

But there will be an Easter miracle that will clear it all up by then.

[BoSoxGal]

https://texags.com/forums/84/topics/310 ... 8k4tqrtO3w

I have been reading as much medical stuff as I can find on the presentation of the illness - this post echoes much of what I’ve found elsewhere about the sepsis occurring in many patients, triggered by cytokine storm. I’m sharing some more info for people about what that is (from wiki) because most won’t have heard of it before. It’s the thing that should have healthy young people stop taking this virus so lightly.

Cytokine release syndrome (CRS) is a form of systemic inflammatory response syndrome that can be triggered by a variety of factors such as infections and certain drugs.[3] It occurs when large numbers of white blood cells are activated and release inflammatory cytokines, which in turn activate yet more white blood cells. CRS is also an adverse effect of some monoclonal antibody drugs, as well as adoptive T-cell therapies.[4][5] Severe cases have been called cytokine storms.[2]

. . .

CRS occurs when large numbers of white blood cells, including B cells, T cells, natural killer cells, macrophages, dendritic cells, and monocytes are activated and release inflammatory cytokines, which in turn activate yet more white blood cells.[4] These cells are activated by infected cells that die by apoptosis or necrosis.[7]

This can occur when the immune system is fighting pathogens, as cytokines signal immune cells such as T-cells and macrophages to travel to the site of infection. In addition, cytokines activate those cells, stimulating them to produce more cytokines.[8]

. . .

The first reference to the term cytokine storm in the published medical literature appears to be by Ferrara et al. in 1993 in a discussion of graft vs. host disease; a condition in which the role of excessive and self-perpetuating cytokine release had already been under discussion for many years.[14][15] The term next appeared in a discussion of pancreatitis in 2002, and in 2003 it was first used in reference to a reaction to an infection.[14]

It is believed that cytokine storms were responsible for the disproportionate number of healthy young adult deaths during the 1918 influenza pandemic, which killed 50 to 100 million people.[16] In this case, a healthy immune system may have been a liability rather than an asset. Preliminary research results from Taiwan also indicated this as the probable reason for many deaths during the SARS epidemic in 2003.[17] Human deaths from the bird flu H5N1 usually involve cytokine storms as well.[18] Cytokine storm has also been implicated in hantavirus pulmonary syndrome.[19]

. . .

In the 2019–20 coronavirus pandemic, a number of deaths due to COVID-19 have been attributable to cytokine release storms.[22][23][24]